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By November 1, 2022No Comments

Nutrients reduce anemia and low-weight births

  • NAD+ protects against anemia

Nicotinamide adenine dinucleotide (NAD+) protects against heart and circulatory conditions, and doctors have noted that anemia is a factor in these conditions. In this study, doctors measured NAD+ levels in 727 women, average age 43 years.

Overall, women with the lowest levels of NAD+ were more than seven times as likely to have anemia compared to women with the highest levels: less than 27.6 micrometers compared to at least 34.5 micrometers of NAD+; or 19.7 percent anemic vs. 2.7 percent, respectively.

Doctors used hemoglobin—red blood cells—as the measure of anemia, with the low-NAD+ group scoring at or below 130.1 grams per liter of blood (g/L), and the high-NAD+ group scoring at or above 139.8 g/L. The study revealed two types of anemia: small red blood cells, and too few red blood cells, both of which declined as NAD+ levels increased.


  • Multivitamin-mineral reduced low-weight births

About one in every six children worldwide is born weighing less than 5 lb. 8 oz. This six-year study followed 96,341 Botswanan women, 22 percent with HIV, who began taking nutritional supplements before the 24th week of pregnancy. One group took iron alone, another took folic acid alone, a third took these two together, and a fourth added a multivitamin-mineral. The multi-nutrient included vitamins A, C, D, E, B1, B2, B3, B6 and B12, plus copper, iodine, selenium, and zinc.

Overall, low birth weights decreased from a high of 16.92 percent for folic acid alone, to 12.7 percent for iron alone, to 11.46 percent for folic acid plus iron. Women in the multivitamin-mineral group had 10.48 percent low-weight births, as well as fewer preterm births and caesarean deliveries compared to all other groups. Women with HIV had the greatest rate of improvement from folic acid alone through the combined multivitamin-mineral treatment.

Reference: The Lancet Global Health; 2022, Vol. 10, No. 6, E850-61

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