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Healthy Liver

By December 1, 2022No Comments

Vitamins D and E improve liver function

  • What is non-alcoholic fatty liver disease?

When excessive fat builds up in the liver without a clear cause, the condition is called non-alcoholic fatty liver disease (NAFLD). Obesity and type 2 diabetes, as well as overweight and metabolic syndrome, are factors that increase chances. Treatment includes weight loss through diet and

  • Vitamin E improved NAFLD

In this study, 100 people with NAFLD took 300 mg of delta-tocotrienol vitamin E or 268 mg of alpha-tocopherol vitamin E, twice per day. The delta-tocotrienol group began to see improvements at 24 weeks that took the alpha-tocopherol group 48 weeks to realize.

At 48 weeks, those taking delta-tocotrienol had lost about 10 pounds of body weight compared to 8 pounds for alpha-tocopherol and saw about 25 percent greater improvements in waist circumference and BMI scores compared to alpha-tocopherol. Triglycerides, high-sensitivity C-reactive protein and other inflammatory factors, blood sugar and fatty acid metabolism also improved in both groups. Liver cell longevity and function benefited from both forms of vitamin E, but the delta-tocotrienol group saw greater improvement.


  • Vitamin D improved liver function in women

In this study, 22 overweight women with NAFLD, aged 20 to 40, took either a placebo or 2,000 IU of vitamin D per day. Before and after the six-week study, participants performed a treadmill session, called Eccentric Exhaustive Exercise, designed to contract, and exhaust the muscles, and that would temporarily raise levels of enzymes that cause liver cell damage.

After the six-week test, liver enzyme levels increased in both groups, but significantly less for the group taking vitamin D. Compared to placebo, the vitamin D group also saw lower body weight and fat percentages, better body mass index scores, as well as greater decreases in triglycerides and LDL cholesterol, and greater increases in HDL, the good cholesterol.

Reference: BMC Gastroenterology; 2022, No. 372, s12876-022-02457

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