Nutrients support postmenopausal bone health
- Collagen, calcium, and vitamin D
Calcium and vitamin D have well-known bone benefits, but here doctors wanted to test these nutrients along with collagen in treating osteopenia—the loss of bone density that can precede osteoporosis. In this study, 51 postmenopausal women with osteopenia took 500 mg of calcium plus 400 IU of vitamin D, with or without 5 grams of collagen peptides per day.
After 12 months, compared to calcium and vitamin D alone, the calcium-vitamin D-collagen group saw a 1.96 percent increase in total bone mineral content (BMC) in the support tissues within the tibia, lumbar spine, and hip; and a 1.01 percent BMC increase in the outer surfaces that form the protective layer of these bones.
Doctors said 12 months of collagen with calcium and vitamin D prevented a decline in bone mineral density and a decrease of bone turnover—bone loss—in postmenopausal women with osteopenia.
Reference: Nutrients; 2021, Vol. 13, No. 6, 34072655, Reference: Journal of Clinical Densitometry; 2021.11.011, Published Online
- Tocotrienols slow bone loss
Tocotrienols in the vitamin E family slowed bone loss by reducing systemic inflammation and oxidative stress. This is the first study to show that tocotrienols modify the global biochemistry of the human body to improve bone health, rather than treating a specific bone condition, as has been the focus of prior studies.
In this study, 89 postmenopausal women with osteopenia, average age 60, overweight and otherwise healthy, took a placebo, 300 or 600 mg of tocotrienols per day for 12 weeks. Doctors observed significant metabolic changes during the study, including lower levels of oxidative stress, greater antioxidant capacity—including increased glutathione levels—and a rebalancing of hormones.
Reference: Frontiers in Nutrition; 2021, 766711, Published Online