Resveratrol improved knee function in osteoarthritis
- First study of oral resveratrol for OA
Most standard treatments for osteoarthritis (OA) of the knee focus on relieving pain, but do nothing to slow the progression of the condition, and have many side effects. In this open-label study, 28 people, half with mild, and half with moderate OA of the knee, took 500 mg of resveratrol per day. There was no placebo group.
After 90 days, participants reported significantly improved symptom scores on two standard osteoarthritis questionnaires: VAS and KOOS. The improvements in joint pain, stiffness, and knee function began at 30 days and continued throughout the study. Resveratrol was well-tolerated with no major side effects.
Discussing the findings, doctors said this is the first study to report oral resveratrol, as a single therapy, provides a remarkable improvement in the clinical status of OA of the knee, with the potential to reduce long-term degenerative joint damage.
Reference: BioMed Research International; Volume 2021, Article ID 3668568